SCHEMBL28026162

SCHEMBL28026162

CC(C)Oc1ccccc1C(=O)OC(=O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.60
ALDH1A1 P00352 3/20 0.45
ACHE P22303 1/20 0.45
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
KCNK3 O14649 2/20 0.43
KCNK9 Q9NPC2 2/20 0.43
TSHR P16473 2/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.40
XBP1 P17861 1/20 0.40
KDM4E B2RXH2 3/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PRMT5 O14744 1/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
CA1 P00915 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958806 0.90 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL4332049 0.86 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2942817 0.84 IRAK4 (0.66) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL28233583 0.84 TSHR (0.57) IRAK4ALDH1A1TSHRNPC1LMNA
SCHEMBL1033621 0.83 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL6014143 0.83 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL11465655 0.83 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL7615528 0.83 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL27568908 0.82 IRAK4 (0.58) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL4036585 0.81 IRAK4 (0.66) IRAK4ALDH1A1ACHEIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829757-B A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application 中国科学院化学研究所 2018-04-27 CN disclosed
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed