SCHEMBL4332049

SCHEMBL4332049

CC(C)Oc1ccccc1C(=O)OC(=O)OC(=O)c1ccccc1OC(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.64
ALDH1A1 P00352 3/20 0.47
ACHE P22303 1/20 0.47
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
KCNK3 O14649 2/20 0.45
KCNK9 Q9NPC2 2/20 0.45
KDM4E B2RXH2 4/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
XBP1 P17861 1/20 0.42
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 1/20 0.41
NPC1 O15118 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
ADRA2A P08913 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958806 0.93 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL4342985 0.88 IRAK4 (0.54) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL28026162 0.86 IRAK4 (0.60) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL27568908 0.85 IRAK4 (0.58) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2942817 0.84 IRAK4 (0.66) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL4036585 0.84 IRAK4 (0.66) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL28026643 0.83 IRAK4 (0.57) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL11465655 0.82 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL6014143 0.82 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL1033621 0.82 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed