SCHEMBL28026173

SCHEMBL28026173

CCCCc1cccc(C(=O)OCC(C)C)c1OC(=O)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
TSHR P16473 5/20 0.50
CYP3A4 P08684 3/20 0.42
CA2 P00918 1/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
TP53 P04637 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 2/20 0.39
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28026662 0.88 TSHR (0.47) ALDH1A1TSHRCYP3A4CA2TP53
SCHEMBL28020520 0.82 ALDH1A1 (0.66) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL28213604 0.82 ALDH1A1 (0.51) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL28821652 0.81 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4CA2TP53
SCHEMBL4628579 0.81 TSHR (0.56) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL28026707 0.81 KDM4E (0.47) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL14975061 0.81 TSHR (0.46) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL15547523 0.78 PPARA (0.47) MEN1KMT2AKDM4ERECQLPPARG
SCHEMBL28940104 0.77 ALDH1A1 (0.62) ALDH1A1TSHRCYP3A4CA2PRSS1
SCHEMBL28213172 0.77 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4CA2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed