Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026390 | 0.88 | KDM4E (0.60) | KDM4EGAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL28026401 | 0.87 | MAPT (0.58) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL3388130 | 0.84 | MAPT (0.76) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL28025828 | 0.81 | ALDH1A1 (0.59) | KDM4EGAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL14848270 | 0.80 | KDM4E (0.66) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL10635597 | 0.79 | KDM4E (0.56) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL1522936 | 0.77 | KDM4E (0.81) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL18582662 | 0.77 | L3MBTL1 (0.71) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL17625298 | 0.76 | F10 (0.58) | KDM4EGAALMNAMAPTPKM | |
| SCHEMBL26310031 | 0.75 | CYP19A1 (0.58) | KDM4EGAALMNAMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945303-A | Preparation method of 3-alkenyl indole compound | UNIV ZHEJIANG TECHNOLOGY | 2015-09-30 | — | — | CN | disclosed |