Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 15/20 | 0.72 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2102012 | 0.84 | PARP10 (1.00) | PARP10PARP4PARP2CA1CA2 | |
| SCHEMBL16800111 | 0.84 | ELANE (0.55) | PARP10KMT2AALDH1A1 | |
| SCHEMBL4458942 | 0.82 | MAPT (0.57) | PARP10KMT2AALDH1A1POLBGLA | |
| Hydrochloric Acid SCHEMBL4963786 | 0.82 | PARP10 (0.96) | PARP10PARP4PARP2CA1CA2 | |
| SCHEMBL11574352 | 0.82 | PARP10 (0.75) | PARP10PARP4PARP2CA1CA2 | |
| SCHEMBL27867048 | 0.81 | PARP10 (0.72) | PARP10PARP4PARP2CA1CA2 | |
| SCHEMBL9045342 | 0.81 | PRSS1 (0.57) | PARP10 | |
| SCHEMBL16800113 | 0.79 | KMT2A (0.45) | PARP10KMT2AALDH1A1POLB | |
| SCHEMBL6616955 | 0.79 | CA1 (0.60) | CA1CA2KMT2AALDH1A1HGFAC | |
| SCHEMBL17911615 | 0.78 | ALDH1A3 (0.41) | PARP10CA1CA2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276550-B | The synthetic method of 2-aryl nitrile thiazole derivative and intermediate thereof | JIUZHOU PHARMACEUTICAL CO., LTD., ZHEJIANG (CN) | 2015-08-19 | — | — | CN | disclosed |