Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.55 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | S100B | P04271 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13716165 | 0.84 | PARP10 (0.66) | PRSS1PRSS2PRSS3ST14F2 | |
| Hydrochloric Acid SCHEMBL9508544 | 0.82 | PARP10 (0.63) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL28026421 | 0.81 | PARP10 (0.72) | PARP10 | |
| SCHEMBL16800113 | 0.79 | KMT2A (0.45) | PARP10ADRA1A | |
| SCHEMBL7390087 | 0.79 | PRSS1 (0.55) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL17911615 | 0.78 | ALDH1A3 (0.41) | PARP10 | |
| SCHEMBL28110160 | 0.77 | CYP1A2 (0.57) | PRSS1PRSS2PRSS3ST14F2 | |
| SCHEMBL16800111 | 0.76 | ELANE (0.55) | PARP10 | |
| SCHEMBL6724722 | 0.76 | PRSS1 (0.59) | PRSS1PRSS2PRSS3ST14F2 | |
| Hydrochloric Acid SCHEMBL9060564 | 0.74 | ST14 (0.57) | PRSS1PRSS2PRSS3ST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690849-A1 | HETEROCYCLE-CONTAINING AMIDINE DERIVATIVES, THEIR PREPARATION AND USE | BOEHRINGER INGELHEIM KG (DE) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994021616-A1 | HETEROCYCLE-CONTAINING AMIDINE DERIVATIVES, THEIR PREPARATION AND USE | BOEHRINGER INGELHEIM KG (DE) | 1994-09-29 | — | — | WO | disclosed |