Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857037 | 0.98 | KDM4E (0.41) | KDM4EPOLBL3MBTL1LMNAGAA | |
| Ammonia Solution, Strong SCHEMBL28281906 | 0.78 | KDM4E (0.40) | KDM4EPOLBL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3903991 | 0.76 | SMN1; SMN2 (0.41) | KDM4EPOLBL3MBTL1LMNAGAA | |
| SCHEMBL841327 | 0.76 | MEN1 (0.48) | KDM4EPOLBL3MBTL1LMNAGAA | |
| SCHEMBL14902252 | 0.76 | CACNA1H (0.35) | KDM4ELMNAGAAALDH1A1KDM6B | |
| SCHEMBL981619 | 0.76 | LMNA (0.38) | KDM4EPOLBL3MBTL1LMNAGAA | |
| SCHEMBL15200246 | 0.76 | KDM4E (0.42) | KDM4EPOLBL3MBTL1LMNAGAA | |
| SCHEMBL295464 | 0.75 | — | — | |
| SCHEMBL3917161 | 0.74 | LMNA (0.37) | KDM4EPOLBL3MBTL1LMNAGAA | |
| Bromide SCHEMBL29450513 | 0.74 | LMNA (0.37) | KDM4EPOLBL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755465-A | Heterocyclic compounds | TAKEDA PHARMACEUTICAL | 2015-07-01 | — | — | CN | disclosed |