SCHEMBL981619

SCHEMBL981619

NCC(=O)NCC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
POLB P06746 2/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.35
KDM4E B2RXH2 4/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
HPGD P15428 1/20 0.35
GAA P10253 1/20 0.34
CACNA1H O95180 1/20 0.34
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1289973 0.98 LMNA (0.37) LMNAPOLBLOXL2SMN1; SMN2KDM4E
Bromide SCHEMBL29450513 0.98 LMNA (0.37) LMNAPOLBLOXL2SMN1; SMN2KDM4E
Trifluoroacetic Acid SCHEMBL1289960 0.91 MMP2 (0.35) LMNAPOLBLOXL2SMN1; SMN2KDM4E
Sulfuric Acid SCHEMBL1289861 0.91 CA1 (0.36) LMNAPOLBLOXL2SMN1; SMN2KDM4E
SCHEMBL26324598 0.81 CACNA1H (0.33) CACNA1H
SCHEMBL1751431 0.81 KDM4E (0.40) LMNAPOLBLOXL2SMN1; SMN2KDM4E
SCHEMBL15607826 0.81 CACNA1H (0.33) CACNA1H
SCHEMBL2035994 0.80 KDM4E (0.39) LMNAPOLBLOXL2SMN1; SMN2KDM4E
Hydrochloric Acid SCHEMBL15792471 0.79 KDM4E (0.39) LMNAPOLBLOXL2SMN1; SMN2KDM4E
SCHEMBL18293043 0.79 CA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214950-A1 METHOD FOR PREPARING FLURALANER HANGZHOU NORMAL UNIVERSITY (CN) 2025-07-03 US claimed
US-12065414-B2 Process for preparation of isoxazoline substituted benzamide compound ZYDUS LIFESCIENCES LIMITED (IN) 2024-08-20 US claimed
CN-114414678-B Analysis method of related impurities of isoxazoline veterinary drug intermediate ammonium salt 丽珠集团新北江制药股份有限公司 2023-05-30 CN claimed
CN-115536541-A Synthesis method of common intermediate of flurradine and afurane 湖北美天生物科技股份有限公司 2022-12-30 CN claimed
CN-113461653-B Method for preparing fraxidin intermediate, and preparation intermediate and application thereof 洛阳惠中兽药有限公司 2022-09-02 CN claimed
CN-114414678-A Analysis method for related impurities of isoxazoline veterinary drug intermediate ammonium salt 丽珠集团新北江制药股份有限公司 2022-04-29 CN claimed
CN-114315748-A Synthesis method of flurarana 江苏天和制药有限公司 2022-04-12 CN claimed
US-20220064130-A1 PROCESS FOR PREPARATION OF ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND ZYDUS LIFESCIENCES LIMITED (IN) 2022-03-03 US claimed
CN-113896690-A Preparation method of isoxazoline anthelmintic agent fluranide 常州齐晖药业有限公司 2022-01-07 CN claimed
CN-113651765-A Synthesis of afurana 江苏君若药业有限公司 2021-11-16 CN claimed
EP-2470007-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF Corporation (US) 2012-07-04 EP claimed
WO-2012084670-A1 PESTICIDAL ACTIVE MIXTURES COMPRISING PYRAZOLE COMPOUNDS BASF SE (DE) 2012-06-28 WO claimed
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION (US) 2012-06-14 US claimed
JP-4805909-B2 2011-11-02 JP claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 WO claimed
WO-2010070068-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2010-06-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE LMNA 409/4885POLB 3106/4885LOXL2 778/4885
US-12065414-B2 Process for preparation of isoxazoline substituted benzamide compound CYP3A7, CYP3A4, CYP4X1 LMNA 2145/4885POLB 1127/4885LOXL2 2737/4885
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE LMNA 2319/4885POLB 4588/4885LOXL2 1300/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 LMNA 1606/4885POLB 4662/4885LOXL2 997/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 LMNA 3123/4885POLB 4409/4885LOXL2 3630/4885
US-20220064130-A1 PROCESS FOR PREPARATION OF ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND CYP3A7, CYP3A4, CYP4X1 LMNA 2145/4885POLB 1127/4885LOXL2 2737/4885
US-20250214950-A1 METHOD FOR PREPARING FLURALANER FFAR4, FFAR2, CYP2A13 LMNA 1256/4885POLB 2057/4885LOXL2 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.