Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729575 | 0.84 | TSHR (0.54) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL582408 | 0.82 | ALDH1A1 (0.53) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL6483048 | 0.81 | TSHR (0.47) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL6483049 | 0.81 | TSHR (0.47) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL1532124 | 0.81 | TSHR (0.50) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL13889265 | 0.81 | TSHR (0.50) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL27642229 | 0.81 | TSHR (0.50) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL28013511 | 0.79 | TSHR (0.58) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL28015627 | 0.79 | TSHR (0.48) | TSHRMAPK1HIF1ALMNAF2 | |
| SCHEMBL27312808 | 0.79 | PTGS1 (0.51) | TSHRMAPK1HIF1ALMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | claimed |
| CN-104828806-B | A graphene modifier, a graphene reinforced composite material and a preparing method of the graphene reinforced composite material | 东莞劲胜精密组件股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-104828806-A | A graphene modifier, a graphene reinforced composite material and a preparing method of the graphene reinforced composite material | JANUS DONGGUAN PREC COMPONENTS | 2015-08-12 | — | — | CN | claimed |
| CN-109415553-A | The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin | 马萨诸塞大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-104828806-B | A graphene modifier, a graphene reinforced composite material and a preparing method of the graphene reinforced composite material | 东莞劲胜精密组件股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104828806-A | A graphene modifier, a graphene reinforced composite material and a preparing method of the graphene reinforced composite material | JANUS DONGGUAN PREC COMPONENTS | 2015-08-12 | — | — | CN | disclosed |