Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483049 | 0.82 | TSHR (0.47) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28026570 | 0.81 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL2729575 | 0.81 | TSHR (0.54) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL582408 | 0.79 | ALDH1A1 (0.53) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL27642229 | 0.78 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL1532124 | 0.78 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL13889265 | 0.78 | TSHR (0.50) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28013511 | 0.77 | TSHR (0.58) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL27312808 | 0.76 | PTGS1 (0.51) | TSHRLMNAF2ALDH1A1TDP1 | |
| SCHEMBL28015627 | 0.76 | TSHR (0.48) | TSHRLMNAF2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962911-B2 | Pyrrolopyrimidinone derivatives, process of preparation and use | SK CHEMICALS CO., LTD. (KR) | 2005-11-08 | — | — | US | disclosed |