Metacresol

Metacresol

SCHEMBL28026685

Cc1cccc(O)c1.Oc1ccc(Cl)cc1

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.71
CYP1A2 P05177 1/20 0.58
CYP2C19 P33261 1/20 0.58
TSHR P16473 1/20 0.52
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
LMNA P02545 3/20 0.44
ALDH1A1 P00352 2/20 0.44
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CYP3A4 P08684 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metacresol SCHEMBL28155447 0.89 ACHE (0.90) ACHECYP1A2CYP2C19TSHRESR1
Metacresol SCHEMBL8655417 0.88 ACHE (0.71) ACHECYP1A2CYP2C19TSHRESR2
Metacresol SCHEMBL28289101 0.87 ACHE (0.85) ACHECYP1A2CYP2C19TSHRESR1
P-Cresol SCHEMBL30606768 0.85 ACHE (0.81) ACHECYP1A2CYP2C19TSHRESR1
P-Cresol SCHEMBL5509205 0.85 ACHE (0.81) ACHECYP1A2CYP2C19TSHRESR1
Metacresol SCHEMBL11437600 0.84 ACHE (1.00) ACHECYP1A2CYP2C19TSHRESR1
Metacresol SCHEMBL10736 0.84
Metacresol SCHEMBL29352064 0.84
Metacresol SCHEMBL2314567 0.84 ACHE (1.00) ACHECYP1A2CYP2C19TSHRESR1
Metacresol SCHEMBL9774388 0.84 ACHE (1.00) ACHECYP1A2CYP2C19TSHRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207729-A Poly (arylene ether) ether sulfone (PAES) polymer and preparation method thereof 索尔维特殊聚合物美国有限责任公司 2017-09-26 CN disclosed
CN-105377953-A Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA 2016-03-02 CN disclosed
CN-105189612-A Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA 2015-12-23 CN disclosed
CN-105189613-A Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA 2015-12-23 CN disclosed