Metacresol

Metacresol

SCHEMBL8655417

Cc1cccc(O)c1.Clc1ccccc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.71
TSHR P16473 4/20 0.58
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
CYP3A4 P08684 2/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
LMNA P02545 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
ALDH1A1 P00352 2/20 0.44
CA5A P35218 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CA1 P00915 1/20 0.40
GLA P06280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metacresol SCHEMBL28026685 0.88 ACHE (0.71) ACHETSHRCYP1A2CYP2C19CYP3A4
Phenol SCHEMBL28146321 0.88 ACHE (0.58) ACHETSHRCYP1A2CYP2C19CA12
Toluene SCHEMBL27882805 0.88 TSHR (0.71) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL27893633 0.87 ACHE (0.85) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL2535890 0.87 ACHE (0.85) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL8390202 0.87 ACHE (0.85) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL11749131 0.87 ACHE (0.85) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL6234380 0.87 ACHE (0.94) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL7619164 0.85 ACHE (0.81) ACHETSHRCYP1A2CYP2C19CYP3A4
Metacresol SCHEMBL2314567 0.84 ACHE (1.00) ACHETSHRCYP1A2CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117902967-A Synthesis method of m-phenoxy benzaldehyde 江苏格涞思工业科技集团有限公司 2024-04-19 CN disclosed
CN-117343316-A Nylon 12 resin, preparation method and application thereof 万华化学集团股份有限公司 2024-01-05 CN disclosed
CN-107710338-A Partial discharge resistant electrically insulating resin composition 住友精化株式会社 2018-02-16 CN disclosed
CN-107710339-A Partial discharge resistant electrically insulating resin composition 住友精化株式会社 2018-02-16 CN disclosed
US-5753407-A Polyamic acid composition KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-19 US disclosed