Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3523783 | 0.85 | TAAR1 (0.57) | TBXAS1SMN1; SMN2MAP4K4ADRA2C | |
| SCHEMBL31483009 | 0.85 | TAAR1 (0.57) | TBXAS1SMN1; SMN2MAP4K4ADRA2C | |
| Bromide SCHEMBL3907833 | 0.84 | TAAR1 (0.55) | TBXAS1SMN1; SMN2MAP4K4ADRA2C | |
| SCHEMBL3903556 | 0.84 | TBXAS1 (0.52) | TBXAS1MAP4K4PRSS1 | |
| Hydrochloric Acid SCHEMBL1622348 | 0.84 | TAAR1 (0.55) | TBXAS1MAP4K4ADRA2CPRSS1 | |
| Hydrochloric Acid SCHEMBL3903275 | 0.82 | TBXAS1 (0.51) | TBXAS1PRSS1 | |
| SCHEMBL3105876 | 0.81 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11021941 | 0.81 | TBXAS1 (0.47) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5988834 | 0.81 | TBXAS1 (0.50) | TBXAS1PRSS1 | |
| SCHEMBL535547 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854087-A | As P2X7Indole carboxamide derivatives of receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2015-08-19 | — | — | CN | disclosed |