Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13570664 | 0.85 | TBXAS1 (0.50) | TBXAS1FFAR1SMN1; SMN2NR1H4HTR2C | |
| SCHEMBL28027156 | 0.81 | TBXAS1 (0.49) | TBXAS1FFAR1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL1821556 | 0.81 | GABRG2 (0.54) | TBXAS1FFAR1SMN1; SMN2GABRG2GABRB3 | |
| SCHEMBL15212297 | 0.79 | MAOB (0.50) | MAOB | |
| SCHEMBL6490663 | 0.79 | TBXAS1 (0.47) | TBXAS1FFAR1SMN1; SMN2NR1H4GABRG2 | |
| SCHEMBL2536496 | 0.79 | KMT2A (0.54) | TBXAS1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6188582 | 0.78 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL14997657 | 0.78 | TBXAS1 (0.49) | TBXAS1FFAR1SMN1; SMN2NR1H4SLC6A2 | |
| SCHEMBL535547 | 0.78 | TBXAS1 (0.49) | TBXAS1FFAR1SMN1; SMN2NR1H4GABRG2 | |
| SCHEMBL11259709 | 0.78 | FFAR1 (0.52) | TBXAS1FFAR1SMN1; SMN2NR1H4GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160573-A2 | Pyrimidinone derivatives | NYCOMED AS (NO) | 1985-11-06 | — | — | EP | disclosed |