SCHEMBL28027313

SCHEMBL28027313

NN1C(=O)c2cccc3c(N4CCCCC4)ccc(c23)C1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 10/20 0.65
KMT2A Q03164 10/20 0.65
MAPT P10636 4/20 0.65
L3MBTL1 Q9Y468 3/20 0.65
RAB9A P51151 2/20 0.65
MAPK1 P28482 2/20 0.65
NPC1 O15118 1/20 0.65
AVPR1A P37288 1/20 0.65
HTT P42858 5/20 0.64
LMNA P02545 5/20 0.64
USP2 O75604 4/20 0.64
TLR9 Q9NR96 2/20 0.64
POLB P06746 1/20 0.64
CRHBP P24387 1/20 0.64
CRHR2 Q13324 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
ALDH1A1 P00352 3/20 0.62
CASP1 P29466 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
TSHR P16473 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28027890 0.98 MEN1 (0.63) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL28413936 0.95 MEN1 (0.59) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL28027354 0.87 MEN1 (0.51) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL7709609 0.85 KMT2A (0.69) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL7709797 0.83 KMT2A (0.67) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL29655588 0.82 MEN1 (0.77) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL28739194 0.82 MEN1 (0.77) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL17599254 0.81 MEN1 (0.60) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL6311388 0.81 MEN1 (0.81) MEN1KMT2AMAPTL3MBTL1RAB9A
SCHEMBL3421714 0.80 MEN1 (0.59) MEN1KMT2AMAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104792759-B A kind of fluorescent test paper of Rapid Detection of Formaldehyde and preparation method and application 济南大学 2017-06-16 CN claimed
CN-104792759-A Fluorescent test paper capable of rapidly detecting formaldehyde and application of fluorescent test paper UNIV JINAN 2015-07-22 CN claimed
CN-111686699-B Formaldehyde adsorption material and preparation method thereof 宁波方太厨具有限公司 2022-10-14 CN disclosed
CN-111686699-A Formaldehyde adsorption material and preparation method thereof 宁波方太厨具有限公司 2020-09-22 CN disclosed
CN-104792759-B A kind of fluorescent test paper of Rapid Detection of Formaldehyde and preparation method and application 济南大学 2017-06-16 CN disclosed
CN-104792759-A Fluorescent test paper capable of rapidly detecting formaldehyde and application of fluorescent test paper UNIV JINAN 2015-07-22 CN disclosed