Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.69 |
| ▸ | MEN1 | O00255 | 10/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | CASP1 | P29466 | 2/20 | 0.66 |
| ▸ | HBB | P68871 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709797 | 0.98 | KMT2A (0.67) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL7709644 | 0.87 | BRD1 (0.60) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL7712239 | 0.87 | MEN1 (0.72) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL28027313 | 0.85 | MEN1 (0.65) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6311388 | 0.84 | MEN1 (0.81) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL28027890 | 0.83 | MEN1 (0.63) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL28655821 | 0.82 | MEN1 (0.62) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL7732734 | 0.82 | MEN1 (1.00) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL25036807 | 0.82 | KMT2A (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL30274171 | 0.82 | KMT2A (0.56) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | claimed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | claimed |
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016043558-A1 | PHOTO-ACID GENERATING AGENT | HERAEUS MATERIALS KOREA CORPORATION (KR) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016043558-A1 | PHOTO-ACID GENERATING AGENT | HERAEUS MATERIALS KOREA CORPORATION (KR) | 2016-03-24 | — | — | WO | disclosed |
| EP-2998297-A1 | Photo-acid generating compounds, compositions comprising said compounds, composite and process for making said composite as well as uses of said compounds | Heraeus Materials Korea Corporation (KR) | 2016-03-23 | — | — | EP | disclosed |
| EP-2998297-A1 | Photo-acid generating compounds, compositions comprising said compounds, composite and process for making said composite as well as uses of said compounds | Heraeus Materials Korea Corporation (KR) | 2016-03-23 | — | — | EP | disclosed |
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |