Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 11/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865683 | 0.78 | KIF11 (0.43) | KIF11PARP14GABRPGABRDGABRA1 | |
| SCHEMBL208113 | 0.77 | KIF11 (0.63) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL29733506 | 0.77 | KIF11 (0.63) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL30136513 | 0.76 | KIF11 (0.53) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL51674 | 0.75 | KIF11 (0.61) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL191654 | 0.75 | KIF11 (0.61) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL30521516 | 0.75 | KIF11 (0.61) | KIF11BCHEPARP14GABRPGABRD | |
| SCHEMBL12615990 | 0.75 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1250423 | 0.75 | KDM4E (0.42) | BCHEALDH1A1HSD17B10KDM4ECYP1A2 | |
| SCHEMBL11738321 | 0.75 | MAPT (0.38) | PARP14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974141-B | Carbazole tetrazole derivatives and its preparation method and application | 西南大学 | 2017-04-05 | — | — | CN | claimed |
| CN-104974141-A | Carbazole tetrazole derivative as well as preparation method and application thereof | UNIV SOUTHWEST | 2015-10-14 | — | — | CN | claimed |
| CN-104974141-B | Carbazole tetrazole derivatives and its preparation method and application | 西南大学 | 2017-04-05 | — | — | CN | disclosed |
| CN-104974141-B | Carbazole tetrazole derivatives and its preparation method and application | 西南大学 | 2017-04-05 | — | — | CN | disclosed |
| CN-104974141-B | Carbazole tetrazole derivatives and its preparation method and application | 西南大学 | 2017-04-05 | — | — | CN | disclosed |
| CN-104974141-A | Carbazole tetrazole derivative as well as preparation method and application thereof | UNIV SOUTHWEST | 2015-10-14 | — | — | CN | disclosed |
| CN-104974141-A | Carbazole tetrazole derivative as well as preparation method and application thereof | UNIV SOUTHWEST | 2015-10-14 | — | — | CN | disclosed |
| CN-104974141-A | Carbazole tetrazole derivative as well as preparation method and application thereof | UNIV SOUTHWEST | 2015-10-14 | — | — | CN | disclosed |