Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027393 | 0.82 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL28027445 | 0.80 | PTPN1 (0.31) | — | |
| SCHEMBL658198 | 0.78 | PTGS2 (0.31) | PTGS2ALDH1A1MAPTESR2 | |
| SCHEMBL28121903 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL28028015 | 0.70 | — | — | |
| SCHEMBL28028018 | 0.70 | — | — | |
| SCHEMBL28821786 | 0.62 | KDM4E (0.40) | PTGS2ALDH1A1MAPTESR2 | |
| SCHEMBL3603579 | 0.61 | TSHR (0.31) | ALDH1A1 | |
| SCHEMBL3599725 | 0.58 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL28027402 | 0.57 | PTGS2 (0.33) | PTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |