Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027985 | 0.89 | PRKCI (0.35) | PRKCITGFBR1MAP2K4NR1H2NR1H3 | |
| SCHEMBL28027381 | 0.82 | BRD4 (0.39) | — | |
| SCHEMBL28028059 | 0.74 | PRKCI (0.34) | PRKCIS1PR1S1PR3MAP2K4NR1H2 | |
| SCHEMBL28027406 | 0.70 | FFAR1 (0.33) | PRKCIS1PR1S1PR3MAP2K4NR1H2 | |
| SCHEMBL28838506 | 0.70 | PRKCI (0.38) | PRKCITGFBR1MAP2K4NR1H2NR1H3 | |
| SCHEMBL28028011 | 0.69 | BRD4 (0.41) | ALDH1A1 | |
| SCHEMBL28122552 | 0.69 | PRKCI (0.35) | PRKCIS1PR1TGFBR1MAP2K4NR1H2 | |
| SCHEMBL28122540 | 0.68 | PRKCI (0.37) | PRKCITGFBR1MAP2K4NR1H2NR1H3 | |
| SCHEMBL28028084 | 0.68 | TGFBR1 (0.40) | PRKCITGFBR1MAP2K4ALDH1A1CNR2 | |
| SCHEMBL28027986 | 0.67 | MAOA (0.41) | PRKCIMAP2K4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |