Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Cetostearyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Hexanol SCHEMBL27745635 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Decanol SCHEMBL28007952 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Dodecanol SCHEMBL27487450 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL27503558 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Octanol SCHEMBL27745636 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Myristyl Alcohol SCHEMBL28076392 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Lactic Acid SCHEMBL29116772 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Tridecan-1-Ol SCHEMBL27919883 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Cetyl Alcohol SCHEMBL27360822 | 1.00 | LMNA (0.59) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Lactic Acid SCHEMBL567251 | 0.91 | ALDH1A1 (0.55) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117338638-A | Anhydrous cleaning product with temperature sensation | 懿奈(上海)生物科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-111118732-A | Non-woven fabric material for saline-alkali soil and preparation method thereof | 山东胜伟盐碱地科技有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-109498478-A | A kind of fullerene topical composition | 北京福纳康生物技术有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-108852865-A | A kind of fullerene topical composition | 北京福纳康生物技术有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-103432037-B | Clove basil oil skin cream | SHANGHAI YANZI CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2015-08-19 | — | — | CN | claimed |
| CN-103432037-A | Clove basil oil skin cream | SHANGHAI YANZI CHEMICAL SCIENCE & TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-101456812-B | Purification method of lactic acid ester | NANJING HUASHI CHEMICAL CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-102100438-A | Product dispenser | MCNEIL PPC INC | 2011-06-22 | — | — | CN | claimed |
| CN-101456812-A | Purification method of lactic acid ester | NANJING SINO LION CHEMICAL CO (CN) | 2009-06-17 | — | — | CN | claimed |
| CN-117338638-A | Anhydrous cleaning product with temperature sensation | 懿奈(上海)生物科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-111118732-A | Non-woven fabric material for saline-alkali soil and preparation method thereof | 山东胜伟盐碱地科技有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111118732-A | Non-woven fabric material for saline-alkali soil and preparation method thereof | 山东胜伟盐碱地科技有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-101917958-B | powder cosmetic composition | AVON PRODUCTS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-103432037-B | Clove basil oil skin cream | SHANGHAI YANZI CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103432037-B | Clove basil oil skin cream | SHANGHAI YANZI CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-103432037-A | Clove basil oil skin cream | SHANGHAI YANZI CHEMICAL SCIENCE & TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | disclosed |
| CN-103079534-A | \"green\" diester amines and personal care products | CRODA INC | 2013-05-01 | — | — | CN | disclosed |
| CN-102100438-A | Product dispenser | MCNEIL PPC INC | 2011-06-22 | — | — | CN | disclosed |
| CN-101917958-A | Powder cosmetic composition | AVON PROD INC | 2010-12-15 | — | — | CN | disclosed |