Iodide

Iodide

SCHEMBL28028057

C#CCOc1ccccc1.I

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.46
MAOB P27338 11/20 0.54
MAOA P21397 7/20 0.54
GSTP1 P09211 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
KCNA3 P22001 1/20 0.48
CYP1A1 P04798 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP1B1 Q16678 1/20 0.45
MAPT P10636 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
ALDH1A1 P00352 1/20 0.43
RECQL P46063 1/20 0.43
KCNH2 Q12809 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72587 0.98 MAOB (0.56) MAOBMAOAGSTP1CA12CA1
Ammonia Solution, Strong SCHEMBL27782744 0.95 MAOB (0.54) MAOBMAOAGSTP1CA12CA1
Ethylene SCHEMBL28489836 0.93 MAOB (0.53) MAOBMAOAGSTP1CA12CA1
Formaldehyde SCHEMBL28138949 0.91 GSTP1 (0.52) MAOBMAOAGSTP1CA12CA1
Zinc Chloride SCHEMBL27876548 0.89 MAOB (0.50) MAOBMAOAGSTP1CA12CA1
SCHEMBL9729724 0.89 LTA4H (0.55) MAOBMAOAGSTP1CA12CA1
Acetic Acid SCHEMBL28643354 0.86 ALOX15 (0.48) MAOBMAOAGSTP1CA12CA1
Acetone SCHEMBL10336499 0.86 ALOX15 (0.48) MAOBMAOAGSTP1CA12CA1
SCHEMBL5704167 0.85 CA12 (0.63) MAOBMAOAGSTP1CA12CA1
SCHEMBL536433 0.85 MAOB (0.68) MAOBMAOAGSTP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104973999-A Novel method for preparing allene by cesium hydroxide catalysis UNIV HUNAN 2015-10-14 CN claimed