SCHEMBL28028065

SCHEMBL28028065

COCC1(COC)Cc2c(cc(C)c(-c3cccc(C=O)c3)c2C)O1.O=Cc1cccc(B(O)O)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28027450 0.92 BRD4 (0.39) BRD4
SCHEMBL28027980 0.82 BRD4 (0.37) BRD4
SCHEMBL28027417 0.77 PRKCI (0.34)
SCHEMBL28027373 0.69 BRD4 (0.39) BRD4
SCHEMBL28027399 0.69 FFAR1 (0.58)
SCHEMBL28027406 0.68 FFAR1 (0.33)
SCHEMBL28027415 0.65 BRD4 (0.43) BRD4
SCHEMBL28028011 0.65 BRD4 (0.41) BRD4
SCHEMBL28027404 0.64 BRD4 (0.39) BRD4
SCHEMBL157163 0.64 KDM4E (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870429-A Benzofuran derivative, preparation method therefor, and medical application thereof SICHUAN HAISCO PHARMACEUTICAL CO LTD 2015-08-26 CN disclosed