Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027406 | 0.89 | FFAR1 (0.33) | PRKCIMAP2K4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28122552 | 0.84 | PRKCI (0.35) | PRKCIMAP2K4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28122540 | 0.82 | PRKCI (0.37) | PRKCIMAP2K4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28027450 | 0.82 | BRD4 (0.39) | — | |
| SCHEMBL28027376 | 0.77 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL28028065 | 0.77 | BRD4 (0.33) | — | |
| SCHEMBL28027950 | 0.76 | ALDH1A1 (0.35) | PRKCIMAP2K4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28027431 | 0.76 | CD274 (0.42) | PRKCIMAP2K4ALDH1A1CNR2FFAR1 | |
| SCHEMBL28122530 | 0.75 | PRKCI (0.35) | PRKCIMAP2K4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28027986 | 0.71 | MAOA (0.41) | PRKCIMAP2K4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870429-B | Benzofuran derivative, preparation method therefor, and medical application thereof | 四川海思科制药有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104870429-A | Benzofuran derivative, preparation method therefor, and medical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2015-08-26 | — | — | CN | disclosed |