Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 8/20 | 0.63 |
| ▸ | METAP1 | P53582 | 4/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | IL1RN | P18510 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3840035 | 0.98 | METAP2 (0.61) | METAP2METAP1ERAP1ERAP2ANPEP | |
| SCHEMBL5848773 | 0.87 | METAP2 (0.65) | METAP2METAP1ERAP1ERAP2ANPEP | |
| SCHEMBL21458090 | 0.87 | METAP2 (0.65) | METAP2METAP1ERAP1ERAP2ANPEP | |
| SCHEMBL3841264 | 0.87 | METAP2 (0.65) | METAP2METAP1ERAP1ERAP2ANPEP | |
| SCHEMBL5848452 | 0.87 | METAP2 (0.65) | METAP2METAP1ERAP1ERAP2ANPEP | |
| Hydrochloric Acid SCHEMBL9369961 | 0.86 | METAP2 (0.63) | METAP2METAP1ERAP1ERAP2ANPEP | |
| SCHEMBL6342154 | 0.81 | SLC15A1 (0.56) | ANPEPEPHX1 | |
| SCHEMBL10772763 | 0.81 | SLC15A1 (0.56) | ANPEPEPHX1 | |
| SCHEMBL289159 | 0.81 | SLC15A1 (0.56) | ANPEPEPHX1 | |
| SCHEMBL4619659 | 0.81 | SLC15A1 (0.56) | ANPEPEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |