SCHEMBL28028239

SCHEMBL28028239

N#Cc1ccc2[nH]c(S(=O)(=O)c3ccccc3)c(C#N)c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.45
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
BRD4 O60885 1/20 0.41
AR P10275 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CXCR2 P25025 2/20 0.40
CYP19A1 P11511 1/20 0.40
PLA2G1B P04054 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
CSF1R P07333 3/20 0.39
CHUK O15111 1/20 0.39
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39
CCNA2 P20248 1/20 0.39
CDK2 P24941 1/20 0.39
GSK3B P49841 1/20 0.39
CCNA1 P78396 1/20 0.39
CDK5 Q00535 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27954350 0.78 CXCR2 (0.47) FASNMEN1KMT2ACXCR2
SCHEMBL12615337 0.73 BCHE (0.46) MEN1KMT2AL3MBTL1CXCR2CHUK
SCHEMBL9561474 0.72 CYP19A1 (0.55) FASNBRD4CYP19A1GSK3BALDH1A1
SCHEMBL6615449 0.72 BCHE (0.42) FASNMEN1KMT2AARL3MBTL1
SCHEMBL6613775 0.71 BCHE (0.41) MEN1KMT2AARL3MBTL1CXCR2
SCHEMBL6613756 0.69 PADI4 (0.39) FASNL3MBTL1CXCR2GSK3BALDH1A1
SCHEMBL28245369 0.69 PTGS2 (0.48) FASNMEN1KMT2ACXCR2CSF1R
SCHEMBL161783 0.69 HTR6 (0.61) CYP19A1MAPT
SCHEMBL606784 0.68 CHUK (0.68) FASNMEN1KMT2AARL3MBTL1
SCHEMBL29402283 0.68 CHUK (0.68) FASNMEN1KMT2AARL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103709089-B One prepares the method for 3-(4 '-chlorobutyl)-5-cyanoindole NANTONG HENGSHENG FINE CHEMICAL CO., LTD. (CN) 2015-08-19 CN disclosed