Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959591 | 0.85 | XIAP (0.49) | NMUR2NMUR1NPY1RNTSR2NTSR1 | |
| SCHEMBL7874280 | 0.84 | EPHA2 (0.43) | NMUR2NMUR1EPHA2OPRM1OPRK1 | |
| SCHEMBL10701287 | 0.81 | XIAP (0.46) | NMUR2NMUR1NPY1RNTSR2NTSR1 | |
| SCHEMBL10653187 | 0.80 | GRB2 (0.43) | NPY1RNTSR2NTSR1SORT1DPP8 | |
| SCHEMBL10653313 | 0.80 | GRB2 (0.43) | NPY1RNTSR2NTSR1SORT1DPP8 | |
| SCHEMBL5597236 | 0.79 | DPP4 (0.40) | NMUR2NMUR1EPHA2 | |
| SCHEMBL9668394 | 0.79 | DPP4 (0.41) | NPY1RNTSR2NTSR1SORT1DPP8 | |
| SCHEMBL29391363 | 0.78 | GRB2 (0.55) | NMUR2NMUR1EPHA2NTSR2NTSR1 | |
| SCHEMBL30285014 | 0.77 | MAPK8 (0.58) | NMUR2NMUR1NPY1REPHA2NTSR2 | |
| SCHEMBL29978208 | 0.77 | MAPK8 (0.50) | NMUR2NMUR1NPY1RNTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282693-B1 | HUMAN COAGULATION FACTOR VII VARIANTS | NOVO NORDISK HEALTHCARE AG (CH) | 2010-10-20 | — | — | EP | disclosed |