Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 8/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053068 | 0.90 | F2 (0.43) | F2PRSS1PRSS2PRSS3ACE | |
| SCHEMBL2226082 | 0.89 | DPP4 (0.46) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14336163 | 0.86 | DPP4 (0.45) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9603823 | 0.86 | DPP4 (0.44) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7106909 | 0.86 | F2 (0.38) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12955580 | 0.81 | F2 (0.44) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9396036 | 0.81 | DPP4 (0.43) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL12955380 | 0.81 | DPP4 (0.42) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL28899291 | 0.80 | DPP4 (0.39) | DPP4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL2802829 | 0.79 | NMUR2 (0.41) | NMUR2NMUR1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753805-A1 | BIOLOGICAL MOLECULE-REACTIVE HYDROPHILIC SILICONE SURFACE | McMASTER UNIVERSITY (CA) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005111116-A1 | BIOLOGICAL MOLECULE-REACTIVE HYDROPHILIC SILICONE SURFACE | MCMASTER UNIVERSITY (CA) | 2005-11-24 | — | — | WO | disclosed |