Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467426 | 0.83 | MAP3K5 (0.54) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL28184943 | 0.79 | FDPS (0.48) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL2264548 | 0.79 | NCF1 (0.50) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL30961064 | 0.79 | MAPT (0.46) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL41211 | 0.79 | PCSK9 (0.48) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL4587589 | 0.79 | FDPS (0.44) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL30824524 | 0.79 | NCF1 (0.50) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL2338189 | 0.79 | MAPT (0.46) | FDPSMAP3K5PCSK9S1PR3KDM4E | |
| SCHEMBL31381352 | 0.76 | MAP3K5 (0.60) | MAP3K5ROCK1CYP1A2MAPT | |
| SCHEMBL167891 | 0.76 | MAP3K5 (0.60) | MAP3K5ROCK1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118142359-A | Anti-pollution and oxidation-resistant reverse osmosis membrane with low-surface-energy coating and preparation method thereof | 万华化学集团股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118142359-A | Anti-pollution and oxidation-resistant reverse osmosis membrane with low-surface-energy coating and preparation method thereof | 万华化学集团股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-103664787-B | Alkynes heteroaromatic ring compounds and application thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2015-09-09 | — | — | CN | disclosed |