SCHEMBL7061982

SCHEMBL7061982

Cc1ccc(CCBr)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.42
PYCR1 P32322 1/20 0.42
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
RAB9A P51151 2/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TNF P01375 1/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
CASP1 P29466 1/20 0.37
HBB P68871 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 1/20 0.37
NR3C1 P04150 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712517 1.00 TAAR1 (0.42) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL6617097 0.87 PYCR1 (0.40) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL6547406 0.85 TAAR1 (0.48) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL11863773 0.84 TAAR1 (0.43) TAAR1ALDH1A1TDP1TP53SMN1; SMN2
SCHEMBL18007054 0.84 PYCR1 (0.38) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL10934302 0.82 TAAR1 (0.63) TAAR1ALDH1A1KDM4ETDP1TP53
SCHEMBL29712514 0.82 TAAR1 (0.63) TAAR1ALDH1A1KDM4ETDP1TP53
SCHEMBL29783360 0.81 ALDH1A1 (0.46) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL1721087 0.81 ALDH1A1 (0.46) TAAR1PYCR1ALDH1A1KDM4ETDP1
SCHEMBL9123696 0.80 TAAR1 (0.41) TAAR1ALDH1A1KDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4492798-A CARBONYLATION OF ARLALKYL HALIDE WITH CARBON MONOXIDE IN THE PRESE ETHYL CORPORATION (US) 1985-01-08 US claimed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
CN-101671240-B Method for preparing 2,2-dimethyl-3-hydrocinnnamic aldehyde and derivative thereof SHANGHAI INST TECHNOLOGY 2013-06-19 CN disclosed
CN-101671240-A Method for preparing 2,2-dimethyl-3-hydrocinnnamic aldehyde and derivative thereof SHANGHAI INST TECHNOLOGY 2010-03-17 CN disclosed
EP-0937703-B1 METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2003-05-21 EP disclosed
US-6348617-B1 REACTING PYRUVIC ACID COMPOUND IN WATER WITH AMMONIUM OR ALKALI METAL BISULFITE TO GIVE AQUEOUS SOLUTION OF BISULFITE ADDUCT, ISOLATING BY PHASE SEPARATION, OPTIONALLY USING HYDROPHOBIC SOLVENT, CONTACTING WITH ACID TO DECOMPOSE ADDUCT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
EP-0937703-A1 METHOD FOR PURIFYING PYRUVIC ACID COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-08-25 EP disclosed
US-5075488-A Fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-24 US disclosed
EP-0128006-B1 A SOIL-DISEASE-CONTROLLING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed
US-4981619-A CARBONYLATION, REDUCTION, FROM HALIDES RHONE POULENC SPECIALITIES CHIMIQUES (FR) 1991-01-01 US disclosed
US-4709052-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
EP-0134216-A4 PROCESS FOR PREPARING -g(a)-KETO-CARBOXYLIC ACIDS. ETHYL CORP (US) 1985-07-01 EP disclosed
EP-0134216-A1 PROCESS FOR PREPARING $g(a)-KETO-CARBOXYLIC ACIDS ETHYL CORPORATION (US) 1985-03-20 EP disclosed
US-4492798-A CARBONYLATION OF ARLALKYL HALIDE WITH CARBON MONOXIDE IN THE PRESE ETHYL CORPORATION (US) 1985-01-08 US disclosed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
WO-1984002699-A1 PROCESS FOR PREPARING alpha-KETO-CARBOXYLIC ACIDS ETHYL CORP (US) 1984-07-19 WO disclosed
US-4353900-A HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS SYNTEX (U.S.A.) INC. (US) 1982-10-12 US disclosed
US-4249938-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-02-10 US disclosed
US-3962357-A FROM SUBSTITUTED ETHYLTOLUENE, CONTINUOUS, SINGLE STEP ROHM AND HAAS COMPANY (US) 1976-06-08 US disclosed