Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 7/20 | 0.45 |
| ▸ | ESR1 | P03372 | 7/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885750 | 0.83 | ACHE (0.42) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL8385836 | 0.82 | ESR2 (0.47) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL133674 | 0.82 | HTR2B (0.50) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL9763719 | 0.82 | ESR2 (0.47) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL29366027 | 0.82 | HTR2B (0.50) | ESR2ESR1TYRCHRM1ADRA1A | |
| Hydrochloric Acid SCHEMBL7078662 | 0.80 | HTR2B (0.48) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL27564626 | 0.80 | HTR2B (0.48) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL29465793 | 0.79 | ESR2 (0.49) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL2501926 | 0.79 | ESR2 (0.49) | ESR2ESR1TYRCHRM1ADRA1A | |
| SCHEMBL12453181 | 0.78 | ESR1 (0.45) | ESR2ESR1TYRCHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209448-A | Tricyclic compounds and uses thereof | SK CHEMICALS CO LTD | 2015-12-30 | — | — | CN | disclosed |