Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423819 | 0.79 | PRCP (0.56) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL3453173 | 0.79 | OPRM1 (0.56) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL330238 | 0.78 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL329925 | 0.78 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL329828 | 0.78 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL13977536 | 0.78 | PRCP (0.67) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL4340396 | 0.77 | PRCP (0.61) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL8719925 | 0.76 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL4020963 | 0.76 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL16308969 | 0.76 | PRCP (0.65) | PRCPSLC22A1OPRM1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450079-B | Tetrahydroisoquinoline hydroxy derivatives, its preparation method and medicinal use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2015-07-29 | — | — | CN | disclosed |