Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453173 | 0.84 | OPRM1 (0.56) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL330238 | 0.83 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL329828 | 0.83 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL329925 | 0.83 | OPRM1 (0.57) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL329886 | 0.81 | OPRM1 (0.59) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL9373834 | 0.80 | PRCP (0.51) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL9373842 | 0.80 | PRCP (0.51) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL9373828 | 0.80 | PRCP (0.51) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL28028557 | 0.79 | PRCP (0.58) | PRCPSLC22A1OPRM1GAAALDH1A1 | |
| SCHEMBL8789518 | 0.79 | PRCP (0.50) | PRCPSLC22A1OPRM1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366981-A | N-acyl-substituted azacyclic compounds, processes for their preparaion, and their use as pharmaceuticals | DR LO ZAMBELETTI S.P.A. (IT) | 1994-11-22 | — | — | US | disclosed |
| WO-1992017467-A1 | SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANALGESICS | DR LO. ZAMBELETTI S.P.A. (IT) | 1992-10-15 | — | — | WO | disclosed |
| EP-0502015-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | Dr. Lo. Zambeletti S.p.A. (IT) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991008205-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | DR. LO. ZAMBELETTI S.P.A. (IT) | 1991-06-13 | — | — | WO | disclosed |