Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28028635 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28028634 | 0.85 | KDM4E (0.49) | MAPTGAASMN1; SMN2POLBALDH1A1 | |
| Tert-Butyl Formate SCHEMBL28028636 | 0.85 | KDM4E (0.49) | MAPTGAASMN1; SMN2POLBALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27868028 | 0.85 | MAPT (0.54) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27791266 | 0.81 | HTT (0.36) | KMT2AALDH1A1 | |
| SCHEMBL11876376 | 0.77 | HTR2C (0.52) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL102309 | 0.75 | MEN1 (0.48) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL14377108 | 0.75 | MAPT (0.63) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL28028630 | 0.74 | MEN1 (0.51) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL3604196 | 0.73 | MEN1 (0.52) | MEN1KMT2AMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438991-B | Carbinol compounds having a heterocyclic linker | KOWA CO.,LTD. (JP) | 2015-08-26 | — | — | CN | disclosed |