Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | BRD1 | O95696 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28028634 | 1.00 | KDM4E (0.49) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| Tert-Butyl Formate SCHEMBL28028633 | 0.85 | MEN1 (0.46) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28028635 | 0.85 | MEN1 (0.46) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27851003 | 0.83 | KDM4E (0.61) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| Tert-Butyl Formate SCHEMBL27769927 | 0.80 | HTR2C (0.37) | BRPF1BRD1BRD4BRPF3GAA | |
| Tert-Butyl Formate SCHEMBL28794366 | 0.73 | KDM4E (0.44) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL105500 | 0.73 | SMARCA2 (0.55) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL5742221 | 0.72 | OPRD1 (0.46) | NPC1ALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL5745273 | 0.71 | GAA (0.48) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL28028631 | 0.71 | KDM4E (0.52) | KDM4ENPC1ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438991-B | Carbinol compounds having a heterocyclic linker | KOWA CO.,LTD. (JP) | 2015-08-26 | — | — | CN | disclosed |