Phosphoric Acid

Phosphoric Acid

SCHEMBL28028658

CCOOP(=O)(O)O.O=P(O)(O)O

nearest known ligand 0.37

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.36
TSHR P16473 2/20 0.35
LPAR3 Q9UBY5 4/20 0.34
LPAR1 Q92633 2/20 0.34
LPAR2 Q9HBW0 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
FDPS P14324 1/20 0.33
BLM P54132 1/20 0.33
TP53 P04637 1/20 0.32
SMPD1 P17405 4/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL946876 0.97
Ethylene SCHEMBL28354737 0.92 PPARD (0.34) PPARDTSHRLPAR3LPAR1LPAR2
Alcohol SCHEMBL1000951 0.92 PPARD (0.39) PPARDTSHRLPAR3LPAR1LPAR2
Allyl Alcohol SCHEMBL2515647 0.82 TSHR (0.38) PPARDTSHRLPAR3LPAR2
SCHEMBL28494106 0.81
Methacrylic Acid SCHEMBL29215269 0.80 PEPD (0.39)
Acrylic Acid SCHEMBL27634446 0.80 LMNA (0.40) TSHRLPAR3
SCHEMBL3046597 0.80 PPARD (0.37) PPARDTSHRLPAR3LPAR1LPAR2
Choline SCHEMBL28155845 0.79 MEN1 (0.44) PPARD
SCHEMBL1573318 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104780901-B Composition for oral cavity 狮王株式会社 2019-04-26 CN disclosed
CN-104780901-A Oral composition LION CORP 2015-07-15 CN disclosed