Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.38 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103094 | 0.83 | MAPT (0.59) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL103095 | 0.83 | MAPT (0.59) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL10499661 | 0.75 | LMNA (0.44) | ALDH1A1HTR1ALMNAHTTGSK3B | |
| SCHEMBL10494883 | 0.73 | LMNA (0.42) | ALDH1A1HTR1ALMNAHTTGSK3B | |
| SCHEMBL10494863 | 0.72 | LMNA (0.41) | ALDH1A1HTR1ALMNAHTTGSK3B | |
| SCHEMBL6969209 | 0.71 | HTR1A (0.61) | ALDH1A1KDM4EHTR1ALMNAHTT | |
| SCHEMBL6969344 | 0.71 | HTR1A (0.61) | ALDH1A1KDM4EHTR1ALMNAHTT | |
| SCHEMBL10575662 | 0.71 | LMNA (0.44) | ALDH1A1HTR1ALMNAHTTGSK3B | |
| SCHEMBL25154269 | 0.71 | DRD4 (0.53) | GSK3BMAPT | |
| SCHEMBL10494852 | 0.70 | MAPK1 (0.41) | ALDH1A1LMNAHTTGSK3BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102438991-B | Carbinol compounds having a heterocyclic linker | KOWA CO.,LTD. (JP) | 2015-08-26 | — | — | CN | disclosed |