Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240455 | 0.87 | SKP2 (0.42) | TSHRCA2KDM4ECXCR5SKP2 | |
| SCHEMBL27940588 | 0.81 | TAAR1 (0.47) | CA2SMN1; SMN2 | |
| SCHEMBL11852687 | 0.81 | KCNH2 (0.50) | TSHRKDM4ECXCR5ALDH1A1HSD17B10 | |
| SCHEMBL28296316 | 0.79 | KCNH2 (0.54) | KDM4ECXCR5ALDH1A1HSD17B10KCNH2 | |
| SCHEMBL27563780 | 0.79 | KCNH2 (0.54) | KDM4ECXCR5ALDH1A1HSD17B10KCNH2 | |
| SCHEMBL9695394 | 0.79 | KCNH2 (0.54) | KDM4ECXCR5ALDH1A1HSD17B10KCNH2 | |
| SCHEMBL6737495 | 0.78 | MYC (0.38) | TSHRCA2SMN1; SMN2KDM4ECXCR5 | |
| M-Xylene SCHEMBL29177628 | 0.78 | ACHE (0.50) | TSHRSKP2HPGDALDH1A1NPC1 | |
| SCHEMBL2697159 | 0.78 | TSHR (0.40) | TSHRKDM4ECXCR5SKP2HPGD | |
| SCHEMBL20749239 | 0.78 | CFTR (0.44) | TSHRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955801-A | Substituted diaryl sulfonamides and uses thereof | NOVOMEDIX LLC | 2015-09-30 | — | — | CN | disclosed |