Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MB | P02144 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784355 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL14546864 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL5544653 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL669442 | 0.84 | EPHX2 (0.70) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL2081375 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1MAPK1TDP1 | |
| SCHEMBL16349508 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL28459398 | 0.82 | EPHX2 (0.52) | SMN1; SMN2L3MBTL1KIF11RAB9AEPHX2 | |
| SCHEMBL21047664 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL28459444 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTMAPK1ALDH1A1MAPT | |
| Nitrogen SCHEMBL28799837 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829420-B | A kind of method that directly aryl diazonium salts is carried out seven fluorine isopropylations by hexafluoropropene | 中国科学院上海有机化学研究所 | 2016-09-14 | — | — | CN | disclosed |
| CN-104829420-A | Method for carrying out direct heptafluoro-isopropylation on aryl diazo salts through hexafluoropropylene | SHANGHAI INST ORGANIC CHEM | 2015-08-12 | — | — | CN | disclosed |