Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MB | P02144 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028708 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL9784355 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL14546864 | 0.85 | SMN1; SMN2 (0.71) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL669442 | 0.84 | EPHX2 (0.70) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL2081375 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1MAPK1TDP1 | |
| SCHEMBL2096237 | 0.82 | EPHX2 (0.52) | SMN1; SMN2L3MBTL1RAB9AEPHX2KIF11 | |
| SCHEMBL2096233 | 0.82 | EPHX2 (0.52) | SMN1; SMN2HTTMAPK1KMT2AMEN1 | |
| SCHEMBL16349508 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL21047664 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2HTTL3MBTL1MAPK1KMT2A | |
| SCHEMBL2094035 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881386-B1 | AMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2018-03-07 | — | — | EP | disclosed |
| US-9185910-B2 | Amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150189880-A1 | AMIDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-09 | — | — | US | disclosed |
| EP-2881386-A1 | AMIDE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2015-06-10 | — | — | EP | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-7262212-B2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | SMN1; SMN2 3985/4885HTT 4644/4885L3MBTL1 1931/4885 |
| US-20150189880-A1 | AMIDE COMPOUND | H1-3, H1-0, H1-4 | SMN1; SMN2 2598/4885HTT 2431/4885L3MBTL1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.