Bicarbonate

Bicarbonate

SCHEMBL28028781

B.O=C(O)O.[NaH].[NaH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28879329 1.00
Bicarbonate SCHEMBL8209384 0.93 CA1 (0.83)
Bicarbonate SCHEMBL7705691 0.93 CA1 (0.83)
Bicarbonate SCHEMBL294626 0.93 CA1 (0.83)
Bicarbonate SCHEMBL308226 0.93
Bicarbonate SCHEMBL5836395 0.93 CA1 (0.83)
Bicarbonate SCHEMBL10386542 0.93 CA1 (0.83)
Bicarbonate SCHEMBL8000370 0.93 CA1 (0.83)
Bicarbonate SCHEMBL21796220 0.93 CA1 (0.83)
Bicarbonate SCHEMBL10904150 0.93 CA1 (0.83)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110944629-B Enzyme-triggered carbon monoxide release molecules 乔治亚州立大学研究基金会股份有限公司 2024-04-09 CN disclosed
CN-104961711-A Preparation method of (S)-3-hydroxytetrahydrofuran and (R)-3-hydroxytetrahydrofuran CANGZHOU SENARY CHEMICAL SCIENCE TEC CO LTD 2015-10-07 CN disclosed