Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159325 | 0.81 | HRH1 (0.50) | IDO1TDO2GAACYP19A1CNR2 | |
| SCHEMBL26693459 | 0.81 | HRH1 (0.50) | IDO1TDO2GAACYP19A1CNR2 | |
| SCHEMBL14672470 | 0.79 | PRKCA (0.51) | GAATAAR1 | |
| SCHEMBL3910983 | 0.79 | TAAR1 (0.60) | IDO1TDO2GAACYP19A1HRH1 | |
| SCHEMBL17802353 | 0.77 | IDO1 (0.42) | IDO1TDO2GAACYP19A1CNR2 | |
| SCHEMBL9326756 | 0.77 | HPGD (0.50) | HRH1OPRK1HTR2ATRPA1TAAR1 | |
| SCHEMBL193835 | 0.77 | HTR2A (0.52) | HRH1HTR2ATRPA1TAAR1TDP1 | |
| SCHEMBL11085997 | 0.76 | GAA (0.47) | IDO1TDO2GAACYP19A1CNR2 | |
| SCHEMBL777640 | 0.76 | SRC (0.46) | IDO1TDO2GAACYP19A1CNR2 | |
| SCHEMBL24877434 | 0.76 | CES2 (0.42) | IDO1TDO2GAACNR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781256-B | 3,4 pairs of substitution oxazolidinone derivatives and its purposes as the inhibitor of calcium-activated potassium channel | 霍夫曼-拉罗奇有限公司 | 2017-09-29 | — | — | CN | disclosed |
| CN-104781256-A | 3,4-disubstituted oxazolidinone derivatives and their use as inhibitors of the calcium activated potassium channel | HOFFMANN LA ROCHE | 2015-07-15 | — | — | CN | disclosed |