Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.61 |
| ▸ | NOS2 | P35228 | 2/20 | 0.61 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481877 | 0.82 | NOS1 (0.53) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL579924 | 0.76 | NOS1 (1.00) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL19028888 | 0.74 | NOS1 (0.69) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL28089032 | 0.73 | NOS1 (0.67) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL25251690 | 0.72 | NOS1 (0.57) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL4315825 | 0.69 | NOS1 (0.60) | NOS1NOS2PDE10AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9122404 | 0.68 | NOS1 (0.58) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL18414154 | 0.67 | NOS1 (0.50) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL16799953 | 0.66 | PARP1 (0.49) | NOS1NOS2PDE10AMEN1KMT2A | |
| SCHEMBL11326420 | 0.65 | PDE10A (0.61) | NOS1NOS2PDE10AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104869987-A | Methods and compositions for regenerating hair cells and/or supporting cells | MASSACHUSETTS EYE & EAR INFIRM | 2015-08-26 | — | — | CN | disclosed |