SCHEMBL579924

SCHEMBL579924

O=[N+]([O-])c1cccc2cn([N+](=O)[O-])nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 1.00
NOS2 P35228 3/20 1.00
PDE10A Q9Y233 1/20 0.51
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
ALDH1A1 P00352 4/20 0.44
TXNRD1 Q16881 1/20 0.42
TXNRD3 Q86VQ6 1/20 0.42
TXNRD2 Q9NNW7 1/20 0.42
TDP1 Q9NUW8 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
CYP2C19 P33261 2/20 0.41
BLM P54132 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19028888 0.81 NOS1 (0.69) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL28089032 0.80 NOS1 (0.67) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL28028950 0.76 NOS1 (0.61) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL4315825 0.75 NOS1 (0.60) NOS1NOS2PDE10AMEN1KMT2A
Hydrochloric Acid SCHEMBL9122404 0.74 NOS1 (0.58) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL4197934 0.73 NOS1 (0.58) NOS1NOS2MEN1KMT2AALDH1A1
SCHEMBL25251690 0.73 NOS1 (0.57) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL7536750 0.72 NOS1 (0.56) NOS1NOS2MEN1KMT2AALDH1A1
SCHEMBL11326420 0.71 PDE10A (0.61) NOS1NOS2PDE10AMEN1KMT2A
SCHEMBL23199862 0.71 MEN1 (0.67) NOS1NOS2PDE10AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180303734-A1 COMPOSITION FOR SKIN WHITENING COMPRISING AMORPHIGENI AS EFFECTIVE INGREDIENT INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) 2018-10-25 US claimed
EP-2593079-B1 MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2016-11-16 EP claimed
EP-2593077-B1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2016-11-02 EP claimed
CN-103025311-B Menthyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2016-03-16 CN claimed
CN-103025310-B Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2016-01-27 CN claimed
US-9060949-B2 Menthyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-06-23 US claimed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US claimed
US-20130129646-A1 MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-05-23 US claimed
EP-2593077-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES Symrise AG (DE) 2013-05-22 EP claimed
EP-2593079-A2 MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES Symrise AG (DE) 2013-05-22 EP claimed
WO-2010122178-A2 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE GMBH & CO. KG (DE) 2010-10-28 WO claimed
WO-2010097480-A2 MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE GMBH & CO. KG (DE) 2010-09-02 WO claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
WO-2026100838-A1 CHAMAECYPARIS OBTUSA LEAF FERMENTATION PRODUCT FERMENTED WITH GANODERMA APPLANATUM, AND USE THEREOF 대구한의대학교산학협력단 2026-05-15 WO disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
US-6673756-B2 MULTILAYER; CUTTING, JOINING UNDER PRESSURE SYMRISE GMBH & CO. KG (DE) 2004-01-06 US disclosed
EP-1326955-A1 MULTI-PHASE SOAP HAARMANN & REIMER GMBH (DE) 2003-07-16 EP disclosed
US-20020173436-A1 Multilayer; cutting, joining under pressure SYMRISE GMBH & CO. KG (DE) 2002-11-21 US disclosed
WO-2002024857-A1 MULTI-PHASE SOAP HAARMANN & REIMER GMBH (DE) 2002-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 NOS1 848/4885NOS2 886/4885PDE10A 2915/4885
US-20180303734-A1 COMPOSITION FOR SKIN WHITENING COMPRISING AMORPHIGENI AS EFFECTIVE INGREDIENT MC1R, ATG7, TYR NOS1 717/4885NOS2 1210/4885PDE10A 2024/4885
US-20130129646-A1 MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES TYR, CRAT, SUCLG1 NOS1 63/4885NOS2 107/4885PDE10A 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.