Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Orthocresol SCHEMBL16002 | 0.94 | — | — | |
| Orthocresol SCHEMBL170162 | 0.94 | TRPA1 (0.60) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL10419161 | 0.94 | TRPA1 (0.60) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL8710164 | 0.94 | TRPA1 (0.60) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL29395276 | 0.94 | — | — | |
| Orthocresol SCHEMBL714951 | 0.92 | TRPA1 (0.52) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL3890279 | 0.91 | TRPA1 (0.57) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL5481807 | 0.91 | — | — | |
| O-Xylene SCHEMBL4541755 | 0.91 | TSHR (0.62) | TRPA1ATMALDH1A1TDP1TSHR | |
| Orthocresol SCHEMBL11055588 | 0.91 | TRPA1 (0.57) | TRPA1ATMALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870475-B | Anti-complement C1s antibodies and uses thereof | 美国比奥维拉迪维股份有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-108610418-A | Anticomplement C1s antibody and its purposes | 美国比奥维拉迪维股份有限公司 | 2018-10-02 | — | — | CN | disclosed |
| CN-104884088-B | Anti-complement C1s antibodies and uses thereof | 美国比奥维拉迪维股份有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-104884088-A | Anti-complement c1s antibodies and uses thereof | TRUE NORTH THERAPEUTICS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-104870475-A | Anti-complement c1s antibodies and uses thereof | TRUE NORTH THERAPEUTICS INC | 2015-08-26 | — | — | CN | disclosed |