Orthocresol

Orthocresol

SCHEMBL8710164

Cc1ccccc1O.Cc1ccccc1O.Cc1ccccc1O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.60
ATM Q13315 1/20 0.60
ALDH1A1 P00352 7/20 0.56
TDP1 Q9NUW8 3/20 0.56
LMNA P02545 3/20 0.56
TSHR P16473 3/20 0.56
CA2 P00918 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ACHE P22303 2/20 0.56
NPC1 O15118 1/20 0.56
CA12 O43570 1/20 0.56
GMNN O75496 1/20 0.56
EGFR P00533 1/20 0.56
FYN P06241 1/20 0.56
POLB P06746 1/20 0.56
CA3 P07451 1/20 0.56
CYP3A4 P08684 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL10419161 1.00 TRPA1 (0.60) TRPA1ATMALDH1A1TDP1LMNA
Orthocresol SCHEMBL16002 1.00
Orthocresol SCHEMBL170162 1.00 TRPA1 (0.60) TRPA1ATMALDH1A1TDP1LMNA
Orthocresol SCHEMBL29395276 1.00
Orthocresol SCHEMBL2840111 0.97
Orthocresol SCHEMBL3407681 0.97
Orthocresol SCHEMBL2210412 0.97 ALDH1A1 (0.62) TRPA1ATMALDH1A1TDP1LMNA
Orthocresol SCHEMBL11178411 0.97 TRPA1 (0.57) TRPA1ATMALDH1A1TDP1LMNA
Orthocresol SCHEMBL6227970 0.97
Orthocresol SCHEMBL40946 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0840783-A1 MICROORGANISMS THAT DECOMPOSE HALOGENATED HYDROCARBONS AND THEIR USE Toyota Jidosha Kabushiki Kaisha (JP) 1998-05-13 EP disclosed
WO-1997040136-A1 MICROORGANISMS THAT DECOMPOSE HALOGENATED HYDROCARBONS AND THEIR USE TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 1997-10-30 WO disclosed
US-4903119-A Semi-conductor device NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-02-20 US disclosed
US-4554388-A I ON OXIDE CATALYST RHEINISCHE BRAUNKOHLENWERKE AKTIENGESELLSCHAFT (DE) 1985-11-19 US disclosed
US-4267392-A TWO-STEP SEPARATION AND PURIFICATION BY PREFERENTIAL COMPLEXING OF FIRST P-CRESOL THEN M-CRESOL WITH A METAL HALIDE; DECOMPOSITION OF THE SOLID COMPLEX KOPPERS COMPANY, INC. (US) 1981-05-12 US disclosed
US-4197397-A PHENOLS UNIVERSITY OF NOTRE DAME DU LAC (US) 1980-04-08 US disclosed
US-4060515-A Chain-extending nitrile end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-29 US disclosed
US-4058505-A Chain-extending amine end-capped polyimides UNIVERSITY OF NOTRE DAME DU LAC (US) 1977-11-15 US disclosed
US-4026871-A Chain-extending phenolic end-capped polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-4026833-A CROSSLINKED FOAMS UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed