Nitrophenolate

Nitrophenolate

SCHEMBL28029048

O=[N+]([O-])c1ccccc1O.O=[N+]([O-])c1ccccc1O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.65
CTSB P07858 1/20 0.57
HSD17B10 Q99714 2/20 0.54
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 3/20 0.54
TP53 P04637 1/20 0.54
HPGD P15428 1/20 0.54
TSHR P16473 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
KCNMA1 Q12791 1/20 0.53
TDP1 Q9NUW8 4/20 0.52
ALOX15 P16050 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
CXCR2 P25025 1/20 0.49
MAPT P10636 2/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrophenolate SCHEMBL26026 1.00 GPR35 (0.65) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL29360402 1.00 GPR35 (0.65) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL28685886 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL31063576 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL28775726 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL10496084 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL325409 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL10996867 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL16553333 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1
Nitrophenolate SCHEMBL11344901 0.98 GPR35 (0.63) GPR35CTSBHSD17B10ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104958258-A Substance-encapsulating vesicle and process for producing the same JAPAN SCIENCE & TECH AGENCY 2015-10-07 CN disclosed