Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28241649 | 0.84 | MAOA (0.45) | DRD2DRD4DRD3MAOA | |
| Biphenyl SCHEMBL27518037 | 0.83 | HRH3 (0.46) | DRD2DRD4DRD3HRH3ALDH1A1 | |
| SCHEMBL79201 | 0.82 | MAOA (0.47) | DRD2DRD4DRD3MAOAABL1 | |
| SCHEMBL27647887 | 0.82 | TAAR1 (0.43) | DRD2DRD4DRD3HRH3 | |
| Bromide SCHEMBL29027395 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOAABL1 | |
| SCHEMBL27951539 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOAABL1 | |
| SCHEMBL6284681 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOAABL1 | |
| SCHEMBL30532125 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOAABL1 | |
| Bromide SCHEMBL29027396 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOAABL1 | |
| SCHEMBL28215975 | 0.79 | MAOA (0.45) | DRD2DRD4DRD3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961741-A | High-steric hindrance chiral porphyrin, preparation method thereof, and application thereof in metalloporphyrin | UNIV HUAZHONG NORMAL | 2015-10-07 | — | — | CN | disclosed |