Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.61 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029411 | 0.84 | HRH3 (0.63) | HRH3KCNH2 | |
| SCHEMBL1372655 | 0.81 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL28029737 | 0.81 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL28029405 | 0.81 | HRH3 (0.58) | HRH3KCNH2 | |
| SCHEMBL11144982 | 0.77 | HRH3 (0.54) | HRH3 | |
| SCHEMBL5677056 | 0.77 | KEAP1 (0.56) | HRH3KCNH2 | |
| SCHEMBL3089686 | 0.77 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL11397967 | 0.77 | HRH3 (0.54) | HRH3 | |
| SCHEMBL11142730 | 0.77 | KMT2A (0.53) | HRH3 | |
| SCHEMBL1640794 | 0.77 | HRH3 (0.58) | HRH3PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | disclosed |