Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919855 | 1.00 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL28029440 | 1.00 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL5288704 | 0.89 | USP2 (0.51) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL2444420 | 0.89 | USP2 (0.51) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL5287268 | 0.89 | USP2 (0.51) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL23877994 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL1655537 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL22168315 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL31040994 | 0.87 | USP2 (0.50) | USP2SMN1; SMN2RECQLEPHA2NR1H2 | |
| SCHEMBL18689612 | 0.86 | USP2 (0.49) | USP2SMN1; SMN2RECQLEPHA2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903310-A | Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain | ARRAY BIOPHARMA INC | 2015-09-09 | — | — | CN | disclosed |