SCHEMBL28029469

SCHEMBL28029469

CCc1cc(N)ccc1C(=N)N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.42
ACHE P22303 1/20 0.41
MASP2 O00187 1/20 0.39
PLAU P00749 1/20 0.39
THPO P40225 1/20 0.39
PRSS1 P07477 3/20 0.38
PRSS3 P35030 3/20 0.38
F2 P00734 2/20 0.38
APEX1 P27695 2/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 4/20 0.37
MAPT P10636 3/20 0.37
GAA P10253 2/20 0.37
CYP3A4 P08684 2/20 0.37
PRSS2 P07478 2/20 0.37
ESR2 Q92731 1/20 0.37
PTPN1 P18031 1/20 0.37
PLG P00747 1/20 0.37
IDO1 P14902 2/20 0.36
GABRP O00591 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3783154 0.82 PRKCI (0.43) PRKCIACHEAPEX1ALDH1A1KDM4E
SCHEMBL28029502 0.82 GABRP (0.41) PRKCIACHEMASP2PLAUTHPO
SCHEMBL182142 0.78 ALDH1A1 (0.57) PRKCIACHEAPEX1ALDH1A1KDM4E
Acetic Acid SCHEMBL5925619 0.78 MAPT (0.43) PRKCIACHEAPEX1ALDH1A1KDM4E
SCHEMBL6651589 0.78 GAA (0.40) PRKCIACHEAPEX1ALDH1A1KDM4E
SCHEMBL24763960 0.77 PRKCI (0.42) PRKCIACHEAPEX1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL7912933 0.77 ALDH1A1 (0.55) PRKCIACHEAPEX1ALDH1A1KDM4E
SCHEMBL345797 0.74 PRKCI (0.45) PRKCIACHEALDH1A1KDM4EMAPT
SCHEMBL31457341 0.74 CYP3A4 (0.44) PRKCIACHEALDH1A1KDM4EMAPT
SCHEMBL1518931 0.74 CYP3A4 (0.44) PRKCIACHEALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870482-B Molecularly imprinted polymer and its purposes as anti-dandruff agent 莱雅公司 2017-10-24 CN disclosed
CN-104870482-A Molecularly imprinted polymers and their use as antidandruff agents OREAL 2015-08-26 CN disclosed